Neurofibromatosis (NF) is a genetic disorder, which appears neurofibromas of the skin and other body parts. Neurofibroma is like a lump of soft flesh, which is derived from nerve tissue.
Neurofibroma is the growth of Schwann cells and other cells that surround and support neurons edge (peripheral nerves, the nerves that are outside the brain and spinal cord). This growth usually begins after puberty and can be felt as a small lump under the skin.
Approximately one-third of patients do not complain of symptoms and the disease was first diagnosed when the physical examination found a lump under the skin, near the nerves.
In the other one-third of patients with this disease are diagnosed when sufferers seek treatment for cosmetic problems.
The remaining third have a neurological disorder.
Looks spots brown skin on the chest, back, hips, elbows and knees. These spots can be found at the time the child is born or newly arising in infancy.
At the age of 10-15 years began to emerge of various sizes and shapes neurofibromas in the skin. The amount could be less than 10 or be in the thousands.
In some patients, this growth poses a problem within the framework of the body, such as abnormal curvature of the spine (kyphoscoliosis), rib deformities, enlargement of the long bones of the arms and legs as well as abnormalities of the skull and around the eyes.
Neurofibromatosis can on every nerve of the body but is often grown in the spinal nerve roots. Neurofibroma suppress peripheral nerves that interfere with normal function.
Neurofibromas are the nerves in the head can cause blindness, dizziness, deafness and impaired coordination.
The more neurofibromas that grow, the more complex the resulting neurological disorders.
Neurofibromatosis type more rarely neurofibromatosis type 2 (NF2), in which tumor growth occurred in the inner ear (acoustic neuroma). These tumors can cause deafness and sometimes dizzy at the age of 20 years.